Fast-release oxycodone is made use of to take care of average to critical agony, including from surgery or an injuries. OxyContin is frequently reserved for lengthier-Long lasting pain with the late stages of a protracted-expression condition, normally cancer.

Step #three: Near observation and titration are warranted until eventually agony administration is steady on The brand new opioid. Watch clients for signals and signs of opioid withdrawal or for indications of over-sedation/toxicity after converting sufferers to OXYCONTIN.

Monitor sufferers for hazard of compound use Conditions, together with opioid abuse and misuse, and alert them of the risk for overdose and death connected to the use of more CNS depressants which include Liquor and illicit medicine [see DRUG INTERACTIONS].

Stay clear of having grapefruit or consuming grapefruit juice whilst using this medication Except if your physician or pharmacist states you could possibly accomplish that properly. Grapefruit can improve the probability of side effects with this medicine. Check with your doctor or pharmacist for more details.

Advise woman clients of reproductive probable that utilization of OXYCONTIN for an prolonged time period during pregnancy can result in neonatal opioid withdrawal syndrome, which can be existence-threatening Otherwise regarded and dealt with [see WARNINGS AND Safety measures and Use In Certain Populations].

Also, outcomes from a single analyze have shown a backlink between certain delivery defects and the use of opioids by Expecting website Ladies.

For pediatric people over a routine of more than one opioid, estimate the approximate oxycodone dose for each opioid and sum the totals to acquire the approximate OXYCONTIN daily dosage.

In case you skip a dose, skip the missed dose. Get your subsequent dose at the standard time. Usually do not double the dose to capture up.

Throughout unique pharmacokinetic scientific studies, normal plasma oxycodone concentrations for woman topics have been up to twenty five% better than for male topics on the body bodyweight-modified foundation. The reason for this distinction is unidentified [see Use In Unique Populations].

Utilization of OXYCONTIN for an extended time period through here pregnancy may result in withdrawal inside the neonate. Neonatal opioid withdrawal syndrome, contrary to opioid withdrawal syndrome in adults, may very well be life-threatening Otherwise regarded and handled, and needs management As outlined by protocols created by neonatology professionals.

Titrate the dosage of OXYCONTIN slowly but surely in geriatric people and frequently reevaluate the affected person for signs of central anxious system and respiratory melancholy. [see WARNINGS AND PRECAUTIONS].

Considering the fact that oxycodone is utilized for soreness, you are not prone to pass up a dose. Skip any missed dose if it is almost time on your subsequent dose. Will not use read more two doses at just one time.

If you have nausea, it could aid to choose this drug with food items. Request your health practitioner or pharmacist about other approaches to minimize nausea (which include lying down for 1 to 2 hours with as minor head movement as is possible). If nausea lasts, see your health care provider.

The concomitant utilization of OXYCONTIN and CYP3A4 inhibitors can raise the plasma focus of oxycodone, causing improved or prolonged opioid effects.